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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC4A1
All Species:
13.64
Human Site:
S181
Identified Species:
37.5
UniProt:
P02730
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02730
NP_000333.1
911
101792
S181
K
P
A
V
L
T
R
S
G
D
P
S
Q
P
L
Chimpanzee
Pan troglodytes
XP_511548
900
100325
S182
K
P
A
V
L
T
R
S
G
D
P
S
Q
P
L
Rhesus Macaque
Macaca mulatta
XP_001103478
1172
130022
G402
H
V
T
E
P
L
I
G
G
V
P
E
T
R
L
Dog
Lupus familis
XP_532761
1223
134633
G466
H
V
T
E
P
L
I
G
G
V
P
E
T
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P04919
929
103117
S195
K
P
A
V
L
T
R
S
G
G
A
S
E
P
L
Rat
Rattus norvegicus
P23562
927
103154
S195
K
P
A
V
L
T
R
S
G
A
P
S
E
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P15575
922
102205
K188
Q
C
S
D
G
E
Q
K
D
A
D
E
R
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107912
1232
137883
R470
E
P
L
M
G
S
S
R
A
S
Q
D
S
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791964
1247
140119
S464
K
A
N
T
N
G
L
S
N
E
N
Q
N
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.2
49.3
45.7
N.A.
81.3
81.4
N.A.
N.A.
61.8
N.A.
47.8
N.A.
N.A.
N.A.
N.A.
36.4
Protein Similarity:
100
93
62.8
58.5
N.A.
88.1
89.2
N.A.
N.A.
74.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
100
100
20
20
N.A.
80
86.6
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
20
20
N.A.
86.6
93.3
N.A.
N.A.
33.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
45
0
0
0
0
0
12
23
12
0
0
23
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
12
23
12
12
0
0
0
% D
% Glu:
12
0
0
23
0
12
0
0
0
12
0
34
23
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
23
12
0
23
67
12
0
0
0
0
0
% G
% His:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% I
% Lys:
56
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
0
45
23
12
0
0
0
0
0
0
0
78
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
12
0
0
0
12
0
12
0
12
0
0
% N
% Pro:
0
56
0
0
23
0
0
0
0
0
56
0
0
45
0
% P
% Gln:
12
0
0
0
0
0
12
0
0
0
12
12
23
0
0
% Q
% Arg:
0
0
0
0
0
0
45
12
0
0
0
0
12
23
0
% R
% Ser:
0
0
12
0
0
12
12
56
0
12
0
45
12
0
12
% S
% Thr:
0
0
23
12
0
45
0
0
0
0
0
0
23
12
0
% T
% Val:
0
23
0
45
0
0
0
0
0
23
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _